Periodic bursting of cultured cortical neurons in low magnesium: cellular and network mechanisms
- PMID: 8271484
Periodic bursting of cultured cortical neurons in low magnesium: cellular and network mechanisms
Abstract
The origin of the 0.1 Hz bursting of cultured rat cortical neurons in zero Mg2+ was studied by whole-cell recording, fluo-3 Ca2+ imaging, and multi-unit electrode array recording. A model is proposed in which spontaneous synaptic currents act as a random pacemaker.
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