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Clinical Trial
. 1993 Oct 15;34(8):507-14.
doi: 10.1016/0006-3223(93)90192-g.

Methylphenidate increases thought disorder in recent onset schizophrenics, but not in normal controls

D L Levy  1 , M Smith, D Robinson, D Jody, G Lerner, J Alvir, S H Geisler, S R Szymanski, A Gonzalez, D I Mayerhoff, et al.
Affiliations
Clinical Trial

Methylphenidate increases thought disorder in recent onset schizophrenics, but not in normal controls

D L Levy et al. Biol Psychiatry. .

Abstract

The effects of apomorphine and methylphenidate on thought disorder, as measured by the Thought Disorder Index, in schizophrenic patients and in normal controls were evaluated. Methylphenidate, but not apomorphine, increased thought disorder in patients. Neither drug significantly increased thought disorder in controls.

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