Chromosome partition in Escherichia coli

Abstract

The past year has seen important genetic and biochemical advances in our understanding of the mechanisms that are involved in chromosome partition into two daughter cells in Escherichia coli. Topoisomerase IV and XerCD recombinase have been shown to be required for the unlinking of replicated chromosomes. MukB, an alpha-helical coiled-coil protein, has been shown to be involved in chromosome partition, and this is the first candidate for a bacterial motor protein. Another protein, FtsZ, has been shown to form a constriction ring in cell division and may also relate to chromosome partition.