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Comparative Study
. 1978 Dec 16;2(8103):1275-7.
doi: 10.1016/s0140-6736(78)92039-1.

Cancer-specific density changes in lymphocytes after stimulation with phytohaemagglutinin

J A Pritchard, W H Sutherland, J E Seaman, T J Deeley, I H Evans, I J Kerby, K W James, I C Paterson
Comparative Study

Cancer-specific density changes in lymphocytes after stimulation with phytohaemagglutinin

J A Pritchard et al. Lancet. .

Abstract

A fluorescence polarisation technique ("S.C.M. test") for detecting responses to phytohaemagglutinin revealed that the responsive lymphocytes from patients with malignant disease had an abnormal distribution after centrifugation through lymphocyte separation medium. In a small blind series the technique accurately distinguished patients with histologically proven malignancies from those with nonmalignant disease and normal people.

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