Fluctuation of fluorescent material in the rat's and human leucocytes under various situation

Abstract

When modified FALCK-HILLARP technic was applied to blood smears of rat and human specimens, the fluorescence was detected not only in platelets, but in leucocytes. In rat leucocytes and platelets, the bimodal daily rhythm of fluorescent material is observed under physiological condition. The rhythm is modified considerably if animals are exposed to the continuous lighting. The intensity and number of the fluorescent cells in the human smears increased markedly in patients suffering from schizophrenia compared with controls. The content of fluorescent material in leucocytes assumes to be closely related with an activity of the living states.