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. 1993 Nov;72(5 Pt 2):820-1.
doi: 10.1111/j.1464-410x.1993.tb16274.x.

Effects of plasma exchange on sperm antibody levels in males with subfertility

P D Abel  1 , K S Lindsay, R H Lord, S MacGregor, I Floyd, G Williams, C D Pusey
Affiliations

Effects of plasma exchange on sperm antibody levels in males with subfertility

P D Abel et al. Br J Urol. 1993 Nov.

Abstract

Three men with subfertility secondary to sperm antibodies with measurable serum sperm antibody levels underwent a course of 3 plasma exchanges over a period of 1 week. The levels of serum anti-sperm antibodies fell by a mean of 3.3 dilutions. This fall was maintained for approximately 4 weeks, after which there was a return to the original levels. Plasma exchange is time-consuming and relatively expensive but it offers a possible alternative to steroid treatment (with its potential side effects) in men with sperm antibodies and warrants further investigation.

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