Oncogenes, tumor suppressors and viruses in oral squamous carcinoma
- PMID: 8283399
- DOI: 10.1111/j.1600-0714.1993.tb01086.x
Oncogenes, tumor suppressors and viruses in oral squamous carcinoma
Abstract
The pathogenesis of oral squamous cell carcinoma involves recognised carcinogens in tobacco and/or alcohol but other factors, including viruses, may also have a role. This paper reviews the gene changes revealed in oral carcinoma, the evidence implicating viruses, and mechanisms whereby viruses may affect gene function.
Similar articles
-
Oral squamous cell carcinoma: new insights.J Can Dent Assoc. 1997 Jul-Aug;63(7):517-8, 521-5. J Can Dent Assoc. 1997. PMID: 9264211 Review.
-
Oral cancer: new insights into pathogenesis.Dent Update. 1993 Apr;20(3):95-100. Dent Update. 1993. PMID: 8224347 Review.
-
P53 and MDM2 co-expression in tobacco and betel chewing-associated oral squamous cell carcinomas.J Med Dent Sci. 2001 Dec;48(4):113-9. J Med Dent Sci. 2001. PMID: 12160248
-
Current trends in miRNAs and their relationship with oral squamous cell carcinoma.J Oral Pathol Med. 2012 Jul;41(6):433-43. doi: 10.1111/j.1600-0714.2011.01121.x. Epub 2011 Dec 21. J Oral Pathol Med. 2012. PMID: 22188431 Review.
-
Review article: The role of oncogenes, tumour suppressor genes and growth factors in oral squamous cell carcinoma: a case of apoptosis versus proliferation.Oral Dis. 1995 Sep;1(3):172-88. doi: 10.1111/j.1601-0825.1995.tb00181.x. Oral Dis. 1995. PMID: 8705824 Review.
Cited by
-
Molecular pathogenesis of oral squamous carcinoma.Mol Pathol. 2000 Aug;53(4):165-72. doi: 10.1136/mp.53.4.165. Mol Pathol. 2000. PMID: 11040937 Free PMC article. Review.
-
Detection of the Epstein-Barr virus and DNA-topoisomerase II- α in recurrent and nonrecurrent giant cell lesion of the jawbones.Biomed Res Int. 2013;2013:327424. doi: 10.1155/2013/327424. Epub 2013 Jul 15. Biomed Res Int. 2013. PMID: 23956975 Free PMC article.
-
Expression of p53 in leukoplakia and squamous cell carcinoma of the oral mucosa: correlation with expression of Ki67.Clin Mol Pathol. 1996 Jun;49(3):M170-5. doi: 10.1136/mp.49.3.m170. Clin Mol Pathol. 1996. PMID: 16696067 Free PMC article.
-
The significance of Epstein Barr virus (EBV) & DNA topoisomerase II alpha (DNA-Topo II alpha) immunoreactivity in normal oral mucosa, oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC).Diagn Pathol. 2008 Nov 20;3:45. doi: 10.1186/1746-1596-3-45. Diagn Pathol. 2008. PMID: 19021895 Free PMC article.
-
Public health implications of smokeless tobacco use as a harm reduction strategy.Am J Public Health. 2006 Nov;96(11):1934-9. doi: 10.2105/AJPH.2005.075499. Epub 2006 Oct 3. Am J Public Health. 2006. PMID: 17018821 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical