Relation between macrophage migration inhibition and immunity to Brucella abortus in guinea-pigs
- PMID: 828715
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Relation between macrophage migration inhibition and immunity to Brucella abortus in guinea-pigs
Onderstepoort J Vet Res.
1976 Dec.
Abstract
Relation between macrophage migration inhibition and immunity to Brucella abortus in guinea-pigs. Onderstepoort Journal of Veterinary Research 43 (4), 175-184 (1976). A soluble protein antigen was prepared from Brucella melitensis Rev I with which macrophage migration inhibition (MMI) assays were successfully done using guinea-pig peritoneal exudate cells. By comparing the MMI, agglutinin response and immunity of groups and of individual guinea-pigs which had been immunized with either B. melitensis Rev I live vaccine or B. melitensis Rev I inactivated antigen, an association between the MMI and resistance to infection was demonstrated.
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