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. 1976 Dec;43(4):175-84.

Relation between macrophage migration inhibition and immunity to Brucella abortus in guinea-pigs

C M Cameron, J J Van Rensburg, M M Engelbrecht
  • PMID: 828715

Relation between macrophage migration inhibition and immunity to Brucella abortus in guinea-pigs

C M Cameron et al. Onderstepoort J Vet Res. 1976 Dec.

Abstract

Relation between macrophage migration inhibition and immunity to Brucella abortus in guinea-pigs. Onderstepoort Journal of Veterinary Research 43 (4), 175-184 (1976). A soluble protein antigen was prepared from Brucella melitensis Rev I with which macrophage migration inhibition (MMI) assays were successfully done using guinea-pig peritoneal exudate cells. By comparing the MMI, agglutinin response and immunity of groups and of individual guinea-pigs which had been immunized with either B. melitensis Rev I live vaccine or B. melitensis Rev I inactivated antigen, an association between the MMI and resistance to infection was demonstrated.

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