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. 1975 Sep-Oct;270(2):401-4.
doi: 10.1097/00000441-197509000-00025.

Purified and inactivated human hepatitis B vaccine: progress report

M R Hilleman, E B Buynak, R R Roehm, A A Tytell, A U Bertland, G P Lampson

Purified and inactivated human hepatitis B vaccine: progress report

M R Hilleman et al. Am J Med Sci. 1975 Sep-Oct.

Abstract

Developments leading to the preparation and testing for safety and potency of a highly purified inactivated preparation of hepatitis B surface antigen are descirbed. Protective efficacy studies in chimps of a lot of the inactivated hepatitis B vaccine are currently and suitable for clinical trials in man.

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