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Case Reports
. 1993 Dec 1;203(11):1552-5.

Estradiol-17 beta-secreting adrenocortical tumor in a ferret

N S Lipman  1 , R P Marini, J C Murphy, Z Zhibo, J G Fox
Affiliations
  • PMID: 8288478
Free article
Case Reports

Estradiol-17 beta-secreting adrenocortical tumor in a ferret

N S Lipman et al. J Am Vet Med Assoc. .
Free article

Abstract

Severe generalized alopecia and marked vulvar enlargement were observed in a 5-year-old spayed ferret with high serum estradiol concentrations. A neoplastic left adrenal gland was removed. Staining of the neoplastic cells for estradiol was demonstrated by use of immunohistochemistry. Clinical findings in this ferret were typical of adrenal-associated endocrinopathy, a syndrome characterized by increased secretion of adrenocortical hormones by hyperplastic or neoplastic adrenal glands.

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