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Comparative Study
. 1994 Jan;176(2):540-2.
doi: 10.1128/jb.176.2.540-542.1994.

Mutations in the delta subunit influence the assembly of F1F0 ATP synthase in Escherichia coli

A E Stack  1 , B D Cain
Affiliations
Comparative Study

Mutations in the delta subunit influence the assembly of F1F0 ATP synthase in Escherichia coli

A E Stack et al. J Bacteriol. 1994 Jan.

Abstract

Missense mutations affecting Asp-161 and Ser-163 in the delta subunit of F1F0 ATP synthase have been generated. Although most substitutions allowed substantial enzyme function, the delta Asp-161-->Pro substitution resulted in a loss of enzyme activity. The loss of activity was attributable to a structural failure altering assembly of the enzyme complex.

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References

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