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. 1993 Nov-Dec;13(6A):2117-8.

False DNA aneuploidy in canine and human neoplasms

A D Deitch  1 , R W de Vere White, B R Madewell
Affiliations
  • PMID: 8297122

False DNA aneuploidy in canine and human neoplasms

A D Deitch et al. Anticancer Res. 1993 Nov-Dec.

Abstract

In most cases, the appearance of aneuploid peaks in DNA histograms may be an artefact of tissue preparation or it may reflect non-stoichiometric dye binding of a cellular subpopulation rather than true DNA aneuploidy. This report reviews how false DNA aneuploidy can be recognized and eliminated from sample submitted for DNA flow cytometric analysis.

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