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. 1994 Feb;62(2):700-3.
doi: 10.1128/iai.62.2.700-703.1994.

Acquisition of heme iron by Neisseria meningitidis does not involve meningococcal transferrin-binding proteins

N Martel  1 , B C Lee
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Acquisition of heme iron by Neisseria meningitidis does not involve meningococcal transferrin-binding proteins

N Martel et al. Infect Immun. 1994 Feb.

Abstract

Similarities in size between hemin-binding protein 1 (HmBP1) and transferrin-binding protein 1 (TBP1) of Neisseria meningitidis suggest that these proteins are functionally homologous. However, a meningococcal mutant lacking the transferrin-binding proteins retained the capacity to acquire iron from heme and hemoglobin. In immunoblots, hyperimmune polyclonal antiserum against TBP1 did not react with HmBP1.

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