The Mycobacterium bovis 32-kilodalton protein antigen induces human cytotoxic T-cell responses
- PMID: 8300233
- PMCID: PMC186167
- DOI: 10.1128/iai.62.2.726-728.1994
The Mycobacterium bovis 32-kilodalton protein antigen induces human cytotoxic T-cell responses
Abstract
The 30-kDa protein (P32) is a mycobacterial secreted antigen which is homologous in Mycobacterium bovis and M. tuberculosis. In vitro, P32 induced T-cell proliferation. M. tuberculosis- or P32-stimulated T-cell lines lysed macrophages pulsed with P32 or M. tuberculosis, respectively. We conclude that P32 stimulates cytotoxic T cells specifically.
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