Characterization of the trehalose 6,6'-dimycolate surface monolayer by scanning tunneling microscopy
- PMID: 8300239
- PMCID: PMC186174
- DOI: 10.1128/iai.62.2.754-756.1994
Characterization of the trehalose 6,6'-dimycolate surface monolayer by scanning tunneling microscopy
Abstract
The toxicity of trehalose 6,6'-dimycolate (TDM), a glycolipid of mycobacteria, requires presentation as a surface monolayer. Our model of the structure of the TDM monolayer was confirmed and extended by scanning tunneling microscopy. It consists of linear arrays with a periodicity of approximately 90 A (9 nm) that clustered in groups of four to form secondary structures with a periodicity of 360 A (36 nm).
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