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. 1994 Feb;62(2):759-63.
doi: 10.1128/iai.62.2.759-763.1994.

Role of iron, capsule, and toxins in the pathogenicity of Vibrio vulnificus biotype 2 for mice

C Amaro  1 , E G Biosca, B Fouz, A E Toranzo, E Garay
Affiliations

Role of iron, capsule, and toxins in the pathogenicity of Vibrio vulnificus biotype 2 for mice

C Amaro et al. Infect Immun. 1994 Feb.

Abstract

The virulence mechanisms of Vibrio vulnificus biotype 2 have been studied and compared with those of biotype 1 in mice as the experimental animals. Biotype 2 isolates from European eels were as virulent for mice as biotype 1 strains (50% lethal dose, about 10(5) CFU per mouse); a septicemic infection developed in less than 24 h. These strains had several properties in common with biotype 1 organisms including capsule expression, uptake of various iron sources, and production of exoproteins, whose role in mouse virulence has been demonstrated. We also discuss the implication of biotype 2 strains in human infections.

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