Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1993 Dec;28(12):1073-6.
doi: 10.3109/00365529309098312.

Faecal calprotectin: a novel test for the diagnosis of colorectal cancer?

A G Røseth  1 , J Kristinsson, M K Fagerhol, H Schjønsby, E Aadland, K Nygaard, B Roald
Affiliations

Faecal calprotectin: a novel test for the diagnosis of colorectal cancer?

A G Røseth et al. Scand J Gastroenterol. 1993 Dec.

Abstract

Calprotectin, a prominent cytosol protein in neutrophil granulocytes, was present in increased concentrations in stools from 50 of 53 patients with colorectal cancer, 32 of 40 patients with colorectal polyps, and all of 18 patients with gastric cancer. After radical surgery, faecal calprotectin levels reverted to the normal range in all but one patient with colorectal cancer. Calprotectin determinations are simplified by the stability of this protein in stools. Reliable estimates can be obtained in samples of only 5 g. On the basis of data from the literature, the test for calprotectin seems better than that for occult blood for the detection of gastrointestinal neoplasms.

PubMed Disclaimer

Substances

LinkOut - more resources