[Continuous infusion of vancomycin in post-neurosurgical staphylococcal meningitis in adults]
[Article in
French]
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- PMID: 8309908
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[Continuous infusion of vancomycin in post-neurosurgical staphylococcal meningitis in adults]
[Article in
French]
Presse Med.
.
Abstract
Eight adult patients with post-surgery meningitis caused by methicillin-resistant staphylococci were treated with continuous intravenous infusion of vancomycin in mean doses of 50 mg/kg/day. This treatment, which lasted 3 to 6 weeks, was well tolerated by the kidneys and resulted in cure in all cases; its effect on the ear was not evaluated. Stable concentrations of 4 to 7 mg/l in cerebrospinal fluid were obtained after the 48th hour of treatment.
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