Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1993;13(4):169-74.
doi: 10.1007/BF00301266.

Primary antiphospholipid antibody syndrome and cerebral ischemia: report on acute intervention in two cases and literature review with emphasis on therapeutic options

S Braune  1 , R Siekmann, P Vaith, C H Lücking
Affiliations
Review

Primary antiphospholipid antibody syndrome and cerebral ischemia: report on acute intervention in two cases and literature review with emphasis on therapeutic options

S Braune et al. Rheumatol Int. 1993.

Abstract

In two patients with primary antiphospholipid antibody syndrome and acute cerebrovascular ischemic events, local intraarterial fibrinolysis and intravenous heparin therapy, respectively, resulted in a limitation of persisting neurological deficits. On the basis of the 35 case reports available a combination of anticoagulation with warfarin, plus immunosuppression with steroids and/or cyclophosphamide or azathioprine, appears to be the best treatment to prevent further cerebral ischemic events. The therapeutic options are reviewed and discussed.

PubMed Disclaimer

References

    1. Lancet. 1989 Jul 15;2(8655):171 - PubMed
    1. Am J Hematol. 1985 Jul;19(3):265-75 - PubMed
    1. Arch Pathol Lab Med. 1985 Oct;109(10):946-51 - PubMed
    1. Stroke. 1992 Feb;23(2 Suppl):I29-32 - PubMed
    1. Stroke. 1983 May-Jun;14(3):377-9 - PubMed