Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1994 Feb 22;1225(3):338-41.
doi: 10.1016/0925-4439(94)90015-9.

Binding of nuclear proteins to transcription regulatory elements in selenium deficiency

M J Christensen  1 , N W Pusey
Affiliations

Binding of nuclear proteins to transcription regulatory elements in selenium deficiency

M J Christensen et al. Biochim Biophys Acta. .

Abstract

Dietary selenium deficiency in rats increased binding of liver nuclear proteins to DNA regulatory sequences which activate transcription in response to oxidative stress. In contrast, binding to the activator protein-1 control sequence, which is inhibited by oxidation, was decreased in selenium deficiency.

PubMed Disclaimer

Publication types

LinkOut - more resources