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. 1977 Jan 21;195(4275):305-6.
doi: 10.1126/science.831279.

Lateral diffusion in planar lipid bilayers

P F Fahey, D E Koppel, L S Barak, D E Wolf, E L Elson, W W Webb

Lateral diffusion in planar lipid bilayers

P F Fahey et al. Science. .

Abstract

Direct measurements by fluorescence correlation spectroscopy of lateral diffusion coefficients of fluorescent lipid analogs in lipid bilaryer membranes indicate self-diffusion coefficients D greater than 10(-7) square centimeters per second for various lipid systems above their reported transition temperatures. Cholesterol in egg lecithin at mole ratio of 1 : 2 reduces D by about twofold, while retained hydrocarbon solvent can increase it by two- to threefold.

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