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Review
. 1993;7(9):473-85.
doi: 10.1111/j.1472-8206.1993.tb00252.x.

Metabotropic glutamate receptors: an original family of G protein-coupled receptors

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Review

Metabotropic glutamate receptors: an original family of G protein-coupled receptors

J Bockaert et al. Fundam Clin Pharmacol. 1993.

Abstract

In 1985, we discovered a new glutamate receptor which was coupled to phospholipase C via a G protein and which was later termed metabotropic glutamate receptor (mGluR). In this review, both the diversity of mGluRs and the cellular events they control are discussed, as well as their roles in physiological regulation and brain function.

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