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Clinical Trial
. 1993;34(2 Suppl):S99-100.
doi: 10.1136/gut.34.2_suppl.s99.

Low dose interferon alfa-2b for chronic hepatitis B in Asian countries

E Mauracher  1
Affiliations
Clinical Trial

Low dose interferon alfa-2b for chronic hepatitis B in Asian countries

E Mauracher. Gut. 1993.

Abstract

In a study of low dose interferon alfa-2b in 587 patients expected to show a good response to treatment, 76-87% patients in different countries had alanine amino-transferase activities returned to normal after four months' treatment, 49-72% were negative for hepatitis B virus (HBV)-DNA, 51-66% were negative for hepatitis B e antigen (HBeAg), and 44-62% were anti-HBe positive. These effects were maintained after nine to 12 months' follow up. Side effects were mild, but led to discontinuation of treatment in 12 patients.

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