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Comparative Study
. 1993 May;16(2):366-73.
doi: 10.1006/geno.1993.1199.

A new member of the cytokine receptor gene family maps on chromosome 21 at less than 35 kb from IFNAR

G Lutfalla  1 , K Gardiner, G Uzé
Affiliations
Comparative Study

A new member of the cytokine receptor gene family maps on chromosome 21 at less than 35 kb from IFNAR

G Lutfalla et al. Genomics. 1993 May.

Abstract

A full-length cDNA corresponding to a gene mapping to the D21S58 locus was cloned. The encoded protein, called CRF2-4, was shown to be a typical class II member of the cytokine receptor family. The gene encoding CRF2-4 spans more than 30 kb. Its intron/exon structure was determined and shown to be conserved with all other members of the cytokine receptor family. The physical distance between the CRF2-4 gene and its IFNAR neighbor has been narrowed to less than 35 kb.

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