Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1993 May;29A(5):419-26.
doi: 10.1007/BF02633992.

Macrophages release melanocyte dendrite extension factor in response to ultra-violet ray

S Suzuki  1 , T Katagiri, T Takeuchi
Affiliations

Macrophages release melanocyte dendrite extension factor in response to ultra-violet ray

S Suzuki et al. In Vitro Cell Dev Biol Anim. 1993 May.

Abstract

Mammalian melanocytes in epidermis extend their dendrites in response to UV ray in vivo in addition to proliferation and pigmentation. We found that cultured macrophages exert a factor in response to UV irradiation and that this factor induces the extension of dendrites of melanocyte. We designated this factor as dendrite extension factor (DEF) and characterized it as a protein. Our results indicate that the molecular weight of DEF is 30,000-100,000 and that it is heat-labile. Macrophages release DEF through transcription and translation. DEF seems to be a novel factor that enhances melanogenesis by UV irradiation.

PubMed Disclaimer

References

    1. J Cell Biol. 1988 Oct;107(4):1611-9 - PubMed
    1. Biochem Biophys Res Commun. 1991 Mar 29;175(3):839-45 - PubMed
    1. JAMA. 1991 Nov 20;266(19):2730-6 - PubMed
    1. J Endocrinol. 1981 Jul;90(1):89-96 - PubMed
    1. Proc Natl Acad Sci U S A. 1988 Jul;85(14):5282-6 - PubMed

MeSH terms

LinkOut - more resources