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. 1977 Jan 3;474(1):69-81.
doi: 10.1016/0005-2787(77)90215-5.

Fractionation of the sequence organization of human DNA by preparative HgCl2/Cs2SO4 density gradients

F P Rinehart, V L Wilson, C W Schmid

Fractionation of the sequence organization of human DNA by preparative HgCl2/Cs2SO4 density gradients

F P Rinehart et al. Biochim Biophys Acta. .

Abstract

Human DNA has been fractionated on preparative HgCl2/Cs2SO4 density gradients. Repetitious sequences are found in DNA components of all base compositions but the (G + C)-rich sequences are enriched for repetitive sequences in (A + T)-rich components are tandemly arranged; those in (G + C)-rich components tend to be interspersed with single copy sequences. It is concluded that the interspersed repetitious sequences have high (G + C) compositions.

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