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Clinical Trial
. 1993 Jul;68(1):112-4.
doi: 10.1038/bjc.1993.295.

Endogenous cortisol exerts antiemetic effect similar to that of exogenous corticosteroids

T J Hursti  1 , M Fredrikson, G Steineck, S Börjeson, C J Fürst, C Peterson
Affiliations
Free PMC article
Clinical Trial

Endogenous cortisol exerts antiemetic effect similar to that of exogenous corticosteroids

T J Hursti et al. Br J Cancer. 1993 Jul.
Free PMC article

Abstract

Lower pre-chemotherapy night time cortisol excretion predicted more severe cisplatin induced nausea and vomiting in 42 ovarian cancer patients receiving ondansetron as a single antiemetic agent. Dexamethasone administration added to the antiemetic effect of ondansetron principally in patients who had low excretion of cortisol.

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References

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