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. 1993 Jun;77(6):366-70.
doi: 10.1136/bjo.77.6.366.

Pathogenesis of acanthamoebic keratitis: hypothesis based on a histological analysis of 30 cases

A Garner  1
Affiliations

Pathogenesis of acanthamoebic keratitis: hypothesis based on a histological analysis of 30 cases

A Garner. Br J Ophthalmol. 1993 Jun.

Abstract

The results of a histopathological study of 30 cases of Acanthamoeba keratitis are construed as indicating a four stage pathogenetic sequence: (1) initial infection, involving breaching of the surface epithelium; (2) keratocyte depletion by the invading trophozoites; (3) inflammatory response mediated by neutrophil polymorphonuclear leucocytes; (4) stromal necrosis attributable to leucocytic activity.

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References

    1. Z Tropenmed Parasitol. 1973 Dec;24(4):385-96 - PubMed
    1. Eye (Lond). 1991;5 ( Pt 5):560-8 - PubMed
    1. Lancet. 1977 Oct 22;2(8043):875-6 - PubMed
    1. Am J Clin Pathol. 1979 Feb;71(2):201-3 - PubMed
    1. Invest Ophthalmol Vis Sci. 1981 Jan;20(1):8-16 - PubMed

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