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. 1993 Jun;59(6):1969-71.
doi: 10.1128/aem.59.6.1969-1971.1993.

Cloning of the gene encoding Streptococcin A-FF22, a novel lantibiotic produced by Streptococcus pyogenes, and determination of its nucleotide sequence

W L Hynes  1 , J J Ferretti, J R Tagg
Affiliations

Cloning of the gene encoding Streptococcin A-FF22, a novel lantibiotic produced by Streptococcus pyogenes, and determination of its nucleotide sequence

W L Hynes et al. Appl Environ Microbiol. 1993 Jun.

Abstract

Streptococcin A-FF22 (SA-FF22) is a lantibiotic produced by Streptococcus pyogenes FF22. The nucleotide sequence of the SA-FF22 structural gene (scnA) was determined and shown to encode a 51-amino-acid prepeptide. The proteolytic processing site of the SA-FF22 prepeptide differs from that which characterizes other type A lantibiotics.

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