Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1993 Jun;59(6):1977-80.
doi: 10.1128/aem.59.6.1977-1980.1993.

Biotransformation of fluorene by the fungus Cunninghamella elegans

J V Pothuluri  1 , J P Freeman, F E Evans, C E Cerniglia
Affiliations

Biotransformation of fluorene by the fungus Cunninghamella elegans

J V Pothuluri et al. Appl Environ Microbiol. 1993 Jun.

Abstract

The metabolism of fluorene, a tricyclic aromatic hydrocarbon, by Cunninghamella elegans ATCC 36112 was investigated. Approximately 69% of the [9-14C]fluorene added to cultures was metabolized within 120 h. The major ethyl acetate-soluble metabolites were 9-fluorenone (62%), 9-fluorenol, and 2-hydroxy-9-fluorenone (together, 7.0%). Similarly to bacteria, C. elegans oxidized fluorene at the C-9 position of the five-member ring to form an alcohol and the corresponding ketone. In addition, C. elegans produced the novel metabolite 2-hydroxy-9-fluorenone.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Anal Chem. 1982 Jan;54(1):106-12 - PubMed
    1. Appl Environ Microbiol. 1992 Mar;58(3):937-41 - PubMed
    1. Environ Health Perspect. 1978 Jun;24:201-8 - PubMed
    1. Appl Environ Microbiol. 1989 Jan;55(1):154-8 - PubMed
    1. Xenobiotica. 1986 Aug;16(8):733-41 - PubMed