Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Jan;15(1):1-6.
doi: 10.1128/iai.15.1.1-6.1977.

Immunogenic activity of a ribosomal fraction obtained from Pasteurella multocida

T Baba

Immunogenic activity of a ribosomal fraction obtained from Pasteurella multocida

T Baba. Infect Immun. 1977 Jan.

Abstract

The cells of P. multocida strain P-1059 were destroyed with the French pressure cell; the ribosomal fraction proven to be homogeneous by analytical ultracentrifugation was obtained from the product by centrifugal fractionation, zonal electrophoresis, and Sephadex G-200 gel filtration. The ribosomal fraction exhibited intense protective antigenicity in mice and chickens, but the lipopolysaccharide (endotoxin) and the other bacterial cell fraction obtained in this experiment did not. Sodium deoxycholate treatment of the ribosomal fraction resulted in only a 13% loss in immunological activity, and ribonuclease treatment caused a 60% loss of activity.

PubMed Disclaimer

References

    1. Infect Immun. 1975 Jun;11(6):1195-202 - PubMed
    1. J Immunol. 1973 Feb;110(2):581-6 - PubMed
    1. Infect Immun. 1972 Sep;6(3):355-63 - PubMed
    1. Infect Immun. 1972 Aug;6(2):156-61 - PubMed
    1. J Bacteriol. 1969 Oct;100(1):140-8 - PubMed

LinkOut - more resources