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. 1993 Apr;39(3-4):243-57.
doi: 10.1016/0169-2607(93)90027-i.

Analysis of variance for 'component stripping' decomposition of multiexponential curves

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Analysis of variance for 'component stripping' decomposition of multiexponential curves

W T Sobol. Comput Methods Programs Biomed. 1993 Apr.

Abstract

An extended analysis of variance is presented for a multiexponential curve fitting procedure, known as 'curve stripping', 'curve peeling', or 'successive subtraction'. In addition to the standard, single variable curves, this analysis includes the two dimensional multiexponential surface analysis. The calculations take into account features required by the graphical user interface that was specifically designed to facilitate the fitting process. The evaluation of the goodness of fit includes an F test (to evaluate the number of components needed to fit the data), and correlation coefficients (to evaluate individual parameters).

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