[Changes in the neuroendocrine and immune state of adaptational homeostasis in normal pregnancy]

Abstract

43 women with physiologically proceeding pregnancy have been examined during 1st, 2nd and 3d terms. The control group consists of 28 practically healthy non-pregnant women. It is stated that during pregnancy essential changes in the function of endocrine glands of mother take place. the appearance of placenta, a new gland of internal secretion, producing choriogonadotropin (CG) as well as the great amount of other hormones of the steroid and protein nature causes essential changes in the regulatory mechanisms underlying the physiological activity of internal secretion glands in mother. The development and early functioning of the internal secretion glands of a fetus promote the hormonal shifts. With the pregnancy development the number of estrogen increases hundred times, relative to their production in non-pregnant women secretion of progesterone and prolactin increase ten times. The functional activity of anterior lobe of the hypophysis, manifesting itself in hypersecretion of adrenocorticotropic hormone inhibition of follicule-stimulating hormone production changes as well. Changes in the functional state of the adrenal gland cortex: cortisole secretion is high are found.