Why are diazepam metabolism and polymorphic S-mephenytoin hydroxylation associated with each other in white and Korean populations but not in Chinese populations?
- PMID: 8338569
- DOI: 10.1038/clpt.1993.77
Why are diazepam metabolism and polymorphic S-mephenytoin hydroxylation associated with each other in white and Korean populations but not in Chinese populations?
Comment in
-
Direct evidence for the higher frequency of CYP2C19 allelic heterozygotes in Chinese subjects than in white subjects.Clin Pharmacol Ther. 1997 Dec;62(6):691-2. doi: 10.1016/S0009-9236(97)90088-6. Clin Pharmacol Ther. 1997. PMID: 9433397 No abstract available.
Comment on
-
Incidence of S-mephenytoin hydroxylation deficiency in a Korean population and the interphenotypic differences in diazepam pharmacokinetics.Clin Pharmacol Ther. 1992 Aug;52(2):160-9. doi: 10.1038/clpt.1992.125. Clin Pharmacol Ther. 1992. PMID: 1505151
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
