[Salmonella-Schistosoma interactions]

Abstract

Prolonged or recurrent typhoid fever and mainly salmonella septicaemia usually regarded as minor, or even episodes of salmonelluria are not uncommon in patients infested with Schistosoma spp. In such cases the salmonella infection is often apparently resistant to antibiotic therapy. Schistosoma-salmonella interactions have been described with all species of schistosoma, notably S. haematobium, S. mansoni, S. intercalatum and S. japonicum. The adult worms of schistosoma live in the mesenteric venous plexuses and, in some particular sites, salmonellas are electively stuck onto the outer wall of adult schistosomas. As a result of this, salmonella septicaemia is facilitated and sustained by the schistosomal infestation, and several varieties of salmonella may be involved. These salmonella infections cannot be cured without treatment of the associated schistosomiasis.