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. 1993 Jul 30;261(5121):615-7.
doi: 10.1126/science.8342027.

Functional magnetic resonance imaging of motor cortex: hemispheric asymmetry and handedness

S G Kim  1 , J Ashe, K Hendrich, J M Ellermann, H Merkle, K Uğurbil, A P Georgopoulos
Affiliations

Functional magnetic resonance imaging of motor cortex: hemispheric asymmetry and handedness

S G Kim et al. Science. .

Abstract

A hemispheric asymmetry in the functional activation of the human motor cortex during contralateral (C) and ipsilateral (I) finger movements, especially in right-handed subjects, was documented with nuclear magnetic resonance imaging at high field strength (4 tesla). Whereas the right motor cortex was activated mostly during contralateral finger movements in both right-handed (C/I mean area of activation = 36.8) and left-handed (C/I = 29.9) subjects, the left motor cortex was activated substantially during ipsilateral movements in left-handed subjects (C/I = 5.4) and even more so in right-handed subjects (C/I = 1.3).

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