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. 1977 Jan 6;265(5589):28-32.
doi: 10.1038/265028a0.

T4 Bacteriophage-coded RNA polymerase subunit blocks host transcription and unfolds the host chromosome

K Sirotkin, J Wei, L Snyder

T4 Bacteriophage-coded RNA polymerase subunit blocks host transcription and unfolds the host chromosome

K Sirotkin et al. Nature. .

Abstract

T4 bacteriophage mutants selected for their ability to grow with cytosine in their DNA are defective in host transcriptional shutoff and host chromosome unfolding. The host RNA polymerase purifed from cells infected by such a mutant lacks a small T4-coded subunit.

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