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. 1993 Jul;37(5):481-91.
doi: 10.1016/0022-3999(93)90004-y.

Mood state as a predictor of treatment outcome after in vitro fertilization/embryo transfer technology (IVF/ET)

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Mood state as a predictor of treatment outcome after in vitro fertilization/embryo transfer technology (IVF/ET)

P Thiering et al. J Psychosom Res. 1993 Jul.

Abstract

The association between mood state and treatment outcome after In Vitro Fertilization/Embryo Transfer (IVF/ET) was assessed in a prospective sample of 330 women, of whom 113 were first time participants (inductees) and 217 were repeat cycle women (veterans). Initial evaluation of mood state indicated a significantly higher level of depression amongst veterans than inductees and a significantly greater proportion of veterans (25%) with clinically elevated depression scores compared with inductees (15%) and community norms (approx. 12%). Up to 12 months after initial assessment and after controlling for the number of treatment cycles, a significant difference was observed in the course of pregnancy over time between depressed and non-depressed women. Depressed women exhibited a lower pregnancy rate for the first treatment cycles than non-depressed women. The results and their implications are discussed.

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