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. 1993 Jul-Aug;13(4):845-50.

Cytogenetic changes in 67 cranial and spinal meningiomas: relation to histopathological and clinical pattern

M Doco-Fenzy  1 , P Cornillet, B Scherpereel, B Depernet, S Bisiau-Leconte, D Ferre, M Pluot, J P Graftiaux, J R Teyssier
Affiliations
  • PMID: 8352553

Cytogenetic changes in 67 cranial and spinal meningiomas: relation to histopathological and clinical pattern

M Doco-Fenzy et al. Anticancer Res. 1993 Jul-Aug.

Abstract

The cytogenetic analysis of 67 meningiomas (58 intracranial and 9 spinal tumors) identified chromosomal abnormalities in 63% of cases. When chromosomes involved in numerical and structural changes with a frequency of more than one standard deviation above the mean were considered, distinct cytogenetic patterns could be identified according to sex, anatomical location and histology. The chromosomes more frequently affected were 1, 2, 3, 4, 8, 14, 15, 19, 22, Y. No conclusion could be drawn regarding the prognostic significance of these karyotypic alterations.

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