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. 1977 Jan;29(1):94-7.

Exclusion of chromosomal mosaicism: tables of 90%, 95% and 99% confidence limits and comments on use

E B Hook

Exclusion of chromosomal mosaicism: tables of 90%, 95% and 99% confidence limits and comments on use

E B Hook. Am J Hum Genet. 1977 Jan.

Abstract

Tables specifically tailored to the exclusion of cytogenetic mosaicism at three confidence levels are presented. The consequences of the assumption of independence in application of the binomial theorem to this question are discussed. The tables are most applicable to the number of cells evaluated from cultures in which all mitoses are arrested in the first in vitro division. For long-term cultures the tables are conservatively applicable to the number of separate colonies evaluated. If n cells have been evaluated from phytohemagglutinin stimulated peripheral blood after 72 hr in cultures, the tables are applicable to between n/2 and n cells.

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References

    1. Humangenetik. 1974 May 17;22(2):139-52 - PubMed
    1. Am J Hum Genet. 1976 May;28(3):290-3 - PubMed
    1. Humangenetik. 1975 Sep 20;30(3):251-7 - PubMed

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