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Clinical Trial
. 1993 Sep;61(9):3994-7.
doi: 10.1128/iai.61.9.3994-3997.1993.

Safety, immunogenicity, and excretion pattern of single-dose live oral cholera vaccine CVD 103-HgR in Peruvian adults of high and low socioeconomic levels

E Gotuzzo  1 , B Butron, C Seas, M Penny, R Ruiz, G Losonsky, C F Lanata, S S Wasserman, E Salazar, J B Kaper, et al.
Affiliations
Clinical Trial

Safety, immunogenicity, and excretion pattern of single-dose live oral cholera vaccine CVD 103-HgR in Peruvian adults of high and low socioeconomic levels

E Gotuzzo et al. Infect Immun. 1993 Sep.

Abstract

Groups of 122 Peruvian adults of low socioeconomic level (SEL) and 125 of high SEL received a randomly allocated 5 x 10(9)- or 5 x 10(8)-CFU dose of CVD 103-HgR live oral cholera vaccine or a placebo. The vaccine was well tolerated. Vibriocidal seroconversions occurred in 78% of high-SEL and 72% of low-SEL subjects who ingested the high dose and in 78 and 49%, respectively, of those who received the low dose.

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References

    1. Bull World Health Organ. 1968;38(2):277-85 - PubMed
    1. Vaccine. 1993;11(2):207-12 - PubMed
    1. Bull World Health Organ. 1968;38(5):777-85 - PubMed
    1. J Infect Dis. 1985 Feb;151(2):236-42 - PubMed
    1. J Clin Microbiol. 1985 Feb;21(2):174-9 - PubMed

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