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. 1993 Jul;46(7):1047-54.
doi: 10.7164/antibiotics.46.1047.

Tetrafibricin, a novel fibrinogen receptor antagonist. II. Structural elucidation

T Kamiyama  1 , Y Itezono, T Umino, T Satoh, N Nakayama, K Yokose
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Free article

Tetrafibricin, a novel fibrinogen receptor antagonist. II. Structural elucidation

T Kamiyama et al. J Antibiot (Tokyo). 1993 Jul.
Free article

Abstract

The structure of tetrafibricin, a novel and potent fibrinogen receptor antagonist isolated from the culture broth of Streptomyces neyagawaensis NR0577, was determined. Tetrafibricin has a unique structure containing primary amine, conjugated tetraenoic acid, and polyhydroxy functionalities that is biosynthetically related to the polyene macrolide antibiotics.

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