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. 1977 Jan 31;257(3):281-5.
doi: 10.1007/BF00741844.

Results of reflex photometric determinations of vasoconstriction after topical steroid application. Tachyphylaxis, relative and absolute refractory phase after single and multiple application of steroid

P Altmeyer, C Cremer

Results of reflex photometric determinations of vasoconstriction after topical steroid application. Tachyphylaxis, relative and absolute refractory phase after single and multiple application of steroid

P Altmeyer et al. Arch Dermatol Res (1975). .

Abstract

After a repeated intensive topical application (4-h rhythm), there it is phase already after 28 h in which the cutaneous vessels are insensitive (refractory) to constrictor stimuli due to steroids. This refractory phase lasts for at least 68 h. A single local application of steroid likewise leads to a diminished vasoreactivity for a limited time. The relative refractory phase is limited to 96 h under the given experimental conditions.

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References

    1. Arch Dermatol. 1975 May;111(5):581-3 - PubMed
    1. Arch Dermatol Res. 1976 Mar 10;255(1):43-50 - PubMed
    1. Arch Dermatol Res. 1976 Mar 10;255(1):51-6 - PubMed
    1. Arch Dermatol Forsch. 1973;247(4):379-86 - PubMed