This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!

Skip to main page content

Add to Collections

Your saved search

Name of saved search:

Search terms:

Test search terms

Would you like email updates of new search results?

Yes
No

Email: (change)

Frequency:

Which day?

Which day?

Report format:

Send at most:

Send even when there aren't any new results

Optional text in email:

Your RSS Feed

Review

. 1993 Jun 23:685:237-47.

doi: 10.1111/j.1749-6632.1993.tb35871.x.

Application of X-ray crystallographic methods in the design of purine nucleoside phosphorylase inhibitors

S E Ealick¹, Y S Babu, C E Bugg, M D Erion, W G Guida, J A Montgomery, J A Secrist 3rd

Affiliations

PMID: 8363227
DOI: 10.1111/j.1749-6632.1993.tb35871.x

Review

Application of X-ray crystallographic methods in the design of purine nucleoside phosphorylase inhibitors

S E Ealick et al. Ann N Y Acad Sci. 1993.

. 1993 Jun 23:685:237-47.

doi: 10.1111/j.1749-6632.1993.tb35871.x.

Authors

S E Ealick¹, Y S Babu, C E Bugg, M D Erion, W G Guida, J A Montgomery, J A Secrist 3rd

Affiliation

¹ Section of Biochemistry, Molecular and Cell Biology, Cornell University, Ithaca, New York 14853.

PMID: 8363227
DOI: 10.1111/j.1749-6632.1993.tb35871.x

No abstract available

PubMed Disclaimer

Similar articles

Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors.
Ealick SE, Babu YS, Bugg CE, Erion MD, Guida WC, Montgomery JA, Secrist JA 3rd. Ealick SE, et al. Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11540-4. doi: 10.1073/pnas.88.24.11540. Proc Natl Acad Sci U S A. 1991. PMID: 1763067 Free PMC article.
Structure-based drug design: inhibitors of purine nucleoside phosphorylase.
Montgomery JA. Montgomery JA. Farmaco. 1993 Feb;48(2):297-308. Farmaco. 1993. PMID: 8494600
Determining the structural basis for specificity of ligands using crystallographic screening.
de Azevedo WF Jr, Canduri F, Basso LA, Palma MS, Santos DS. de Azevedo WF Jr, et al. Cell Biochem Biophys. 2006;44(3):405-11. doi: 10.1385/CBB:44:3:405. Cell Biochem Biophys. 2006. PMID: 16679527
[Tight binding transition state analogues of purine nucleoside phosphorylase--meaning, design and properties].
Lewandowicz A. Lewandowicz A. Postepy Biochem. 2004;50(3):218-27. Postepy Biochem. 2004. PMID: 15822751 Review. Polish. No abstract available.
Design of purine nucleoside phosphorylase inhibitors.
Stoeckler JD, Ealick SE, Bugg CE, Parks RE Jr. Stoeckler JD, et al. Fed Proc. 1986 Nov;45(12):2773-8. Fed Proc. 1986. PMID: 3095150 Review.

See all similar articles

Cited by

Molecular docking investigation of the amantadine binding to the enzymes upregulated or downregulated in Parkinson's disease.
Ionescu MI. Ionescu MI. ADMET DMPK. 2020 Jun 15;8(2):149-175. doi: 10.5599/admet.854. eCollection 2020. ADMET DMPK. 2020. PMID: 35300368 Free PMC article.

Publication types

Actions
Actions
Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions

Grants and funding

GM-38823/GM/NIGMS NIH HHS/United States

LinkOut - more resources

Full Text Sources
- Wiley