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. 1977 Jan 15;33(1):20-2.
doi: 10.1007/BF01936728.

N-(5'-Phosphopyridoxyl)-4-aminobutyric acid: a stabel bisubstrate adduct inhibitor of rat brain 4-aminobutyric acid aminotransferase

G Tunnicliff, T T Ngo, A Barbeau

N-(5'-Phosphopyridoxyl)-4-aminobutyric acid: a stabel bisubstrate adduct inhibitor of rat brain 4-aminobutyric acid aminotransferase

G Tunnicliff et al. Experientia. .

Abstract

N-(5'-Phosphophopyridoxyl)-4-aminobutyric acid, a stable adduct of pyridoxal phosphate and 4-aminobutyrate acid, has been shown to be a potent inhibitor of rat brain 4-aminobutyric acid aminotransferase (GABA-T) with a K1 of 1.4 muM.

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References

    1. Int Rev Neurobiol. 1975;17:1-36 - PubMed
    1. Eur J Biochem. 1975 Mar 3;52(1):157-69 - PubMed
    1. Can J Physiol Pharmacol. 1974 Jun;52(3):674-80 - PubMed
    1. Biochim Biophys Acta. 1975 Sep 22;403(1):197-207 - PubMed
    1. Biochem Biophys Res Commun. 1969 May 8;35(3):318-23 - PubMed

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