Does resuscitative hypothermia protect the ischemic brain?

Editorial

M D Ginsberg. Crit Care Med. 1993 Sep.

. 1993 Sep;21(9):1265-6.

doi: 10.1097/00003246-199309000-00005.

No abstract available

Comment in

Resuscitative cerebral hypothermia after cardiac arrest.
Safar P, Bircher NG. Safar P, et al. Crit Care Med. 1994 Oct;22(10):1703-4. Crit Care Med. 1994. PMID: 7924386 No abstract available.

Delay in cooling negates the beneficial effect of mild resuscitative cerebral hypothermia after cardiac arrest in dogs: a prospective, randomized study.
Kuboyama K, Safar P, Radovsky A, Tisherman SA, Stezoski SW, Alexander H. Kuboyama K, et al. Crit Care Med. 1993 Sep;21(9):1348-58. doi: 10.1097/00003246-199309000-00019. Crit Care Med. 1993. PMID: 8370299

Mild Hypothermia Combined with Hydrogen Sulfide Treatment During Resuscitation Reduces Hippocampal Neuron Apoptosis Via NR2A, NR2B, and PI3K-Akt Signaling in a Rat Model of Cerebral Ischemia-Reperfusion Injury.
Dai HB, Xu MM, Lv J, Ji XJ, Zhu SH, Ma RM, Miao XL, Duan ML. Dai HB, et al. Mol Neurobiol. 2016 Sep;53(7):4865-73. doi: 10.1007/s12035-015-9391-z. Epub 2015 Sep 9. Mol Neurobiol. 2016. PMID: 26350917
Resuscitative hypothermia.
Marion DW, Leonov Y, Ginsberg M, Katz LM, Kochanek PM, Lechleuthner A, Nemoto EM, Obrist W, Safar P, Sterz F, Tisherman SA, White RJ, Xiao F, Zar H. Marion DW, et al. Crit Care Med. 1996 Feb;24(2 Suppl):S81-9. Crit Care Med. 1996. PMID: 8608709 Review.
Therapeutic window of selective profound cerebral hypothermia for resuscitation of severe cerebral ischemia in primates.
Liang YM, Jiang JY, Mao Q, Zhang S, Xu W. Liang YM, et al. J Neurotrauma. 2009 Nov;26(11):2107-12. doi: 10.1089/neu.2009.0889. J Neurotrauma. 2009. PMID: 19469689
Resuscitative mild hypothermia as a protective tool in brain damage: is there evidence?
Hachimi-Idrissi S, Huyghens L. Hachimi-Idrissi S, et al. Eur J Emerg Med. 2004 Dec;11(6):335-42. doi: 10.1097/00063110-200412000-00007. Eur J Emerg Med. 2004. PMID: 15542991 Review.
Resuscitative cerebral hypothermia after cardiac arrest.
Safar P, Bircher NG. Safar P, et al. Crit Care Med. 1994 Oct;22(10):1703-4. Crit Care Med. 1994. PMID: 7924386 No abstract available.