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. 1993 Jul;20(7):580-4.
doi: 10.1007/BF00176551.

Dosimetry of iodine-123 iomazenil in humans

N P Verhoeff  1 , E Busemann Sokole, D Hengst, J B Stubbs, E A van Royen
Affiliations

Dosimetry of iodine-123 iomazenil in humans

N P Verhoeff et al. Eur J Nucl Med. 1993 Jul.

Abstract

The distribution of the central benzodiazepine receptor specific ligand iodine-123 iomazenil was investigated in seven human adults from whole-body scans, blood samples and urine collected up to 24 h after injection. Using 12 source organs, the MIRD method was applied to calculate the absorbed radiation dose of the radioligand in various organs. The urinary bladder wall (0.15 mGy/MBq), lower large intestinal wall (0.071 mGy/MBq) testes (0.044 mGy/MBq) and upper large intestined wall (0.038 mGy/MBq) received the highest absorbed doses. The average effective dose equivalent of 123I-IBZM for adults was estimated to be 0.033 mSv/MBq.

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