Flow injection assays with chemiluminescence and bioluminescence detection--a review

Abstract

This paper reviews publications that combine the technique of flow injection (FI) with chemiluminescence (CL) and bioluminescence (BL) detection, from the earliest papers in 1979/80 to mid-1992, and refers exclusively to reactions occurring in solution. Air-segmented systems and liquid chromatography with CL detection are not considered unless FI has been used to pre-optimize the system. The applications have been categorized in terms of the type of CL reaction; there are separate entries for luminol, peroxyoxalate, other CL reactions and BL reactions. Each of the four sections includes a table of applications that lists the analyte, the nature of the reaction, the sample matrix and the limit of detection.