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Case Reports
. 1993 May-Jun;78(3):192-4.

A recently recognized entity associated with the treatment of acute promyelocytic leukemia: the retinoic acid syndrome

T Marinakis  1 , C A Papadimitriou, C Koufos, A Fertakis
Affiliations
  • PMID: 8375752
Case Reports

A recently recognized entity associated with the treatment of acute promyelocytic leukemia: the retinoic acid syndrome

T Marinakis et al. Haematologica. 1993 May-Jun.

Abstract

All-trans-retinoic acid is an effective induction treatment for acute promyelocytic leukemia. Although retinoic acid is well tolerated by the majority of patients with this disease, a potentially fatal complication of this kind of treatment has been reported: "the retinoic acid syndrome". We describe this syndrome, which occurred in one of our patients and was successfully treated by the administration of dexamethasone.

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